diff --git a/homeassistant/components/homeassistant_connect_zbt2/manifest.json b/homeassistant/components/homeassistant_connect_zbt2/manifest.json
index c976c5727a5..c225d6d1c9c 100644
--- a/homeassistant/components/homeassistant_connect_zbt2/manifest.json
+++ b/homeassistant/components/homeassistant_connect_zbt2/manifest.json
@@ -10,7 +10,8 @@
     "bellows",
     "universal_silabs_flasher",
     "zigpy.serial",
-    "serial_asyncio_fast"
+    "serial_asyncio_fast",
+    "serialx"
   ],
   "quality_scale": "bronze",
   "usb": [
diff --git a/homeassistant/components/homeassistant_hardware/manifest.json b/homeassistant/components/homeassistant_hardware/manifest.json
index 552302a45ec..ab1906c92b3 100644
--- a/homeassistant/components/homeassistant_hardware/manifest.json
+++ b/homeassistant/components/homeassistant_hardware/manifest.json
@@ -7,6 +7,7 @@
   "documentation": "https://www.home-assistant.io/integrations/homeassistant_hardware",
   "integration_type": "system",
   "requirements": [
+    "serialx==0.5.0",
     "universal-silabs-flasher==0.1.2",
     "ha-silabs-firmware-client==0.3.0"
   ]
diff --git a/homeassistant/components/homeassistant_sky_connect/manifest.json b/homeassistant/components/homeassistant_sky_connect/manifest.json
index d4d7a967273..ad41ee92e50 100644
--- a/homeassistant/components/homeassistant_sky_connect/manifest.json
+++ b/homeassistant/components/homeassistant_sky_connect/manifest.json
@@ -10,7 +10,8 @@
     "bellows",
     "universal_silabs_flasher",
     "zigpy.serial",
-    "serial_asyncio_fast"
+    "serial_asyncio_fast",
+    "serialx"
   ],
   "usb": [
     {
diff --git a/homeassistant/components/homeassistant_yellow/manifest.json b/homeassistant/components/homeassistant_yellow/manifest.json
index 2fd9b91ca02..31f5b163f92 100644
--- a/homeassistant/components/homeassistant_yellow/manifest.json
+++ b/homeassistant/components/homeassistant_yellow/manifest.json
@@ -11,7 +11,8 @@
     "bellows",
     "universal_silabs_flasher",
     "zigpy.serial",
-    "serial_asyncio_fast"
+    "serial_asyncio_fast",
+    "serialx"
   ],
   "single_config_entry": true
 }
diff --git a/homeassistant/components/zha/manifest.json b/homeassistant/components/zha/manifest.json
index 86731088639..a004ed340ae 100644
--- a/homeassistant/components/zha/manifest.json
+++ b/homeassistant/components/zha/manifest.json
@@ -20,9 +20,10 @@
     "zigpy_zigate",
     "zigpy_znp",
     "zha",
-    "universal_silabs_flasher"
+    "universal_silabs_flasher",
+    "serialx"
   ],
-  "requirements": ["zha==0.0.82"],
+  "requirements": ["zha==0.0.82", "serialx==0.5.0"],
   "usb": [
     {
       "description": "*2652*",
diff --git a/requirements_all.txt b/requirements_all.txt
index 48629e0c56b..80dca838527 100644
--- a/requirements_all.txt
+++ b/requirements_all.txt
@@ -2834,6 +2834,10 @@ sentence-stream==1.2.0
 # homeassistant.components.sentry
 sentry-sdk==1.45.1
 
+# homeassistant.components.homeassistant_hardware
+# homeassistant.components.zha
+serialx==0.5.0
+
 # homeassistant.components.sfr_box
 sfrbox-api==0.1.0
 
diff --git a/requirements_test_all.txt b/requirements_test_all.txt
index 398676cf081..b5b3e453387 100644
--- a/requirements_test_all.txt
+++ b/requirements_test_all.txt
@@ -2373,6 +2373,10 @@ sentence-stream==1.2.0
 # homeassistant.components.sentry
 sentry-sdk==1.45.1
 
+# homeassistant.components.homeassistant_hardware
+# homeassistant.components.zha
+serialx==0.5.0
+
 # homeassistant.components.sfr_box
 sfrbox-api==0.1.0