diff --git a/homeassistant/components/script/__init__.py b/homeassistant/components/script/__init__.py
index dd293726484..8b1e2ce8b30 100644
--- a/homeassistant/components/script/__init__.py
+++ b/homeassistant/components/script/__init__.py
@@ -11,8 +11,9 @@ from typing import TYPE_CHECKING, Any, cast
 from propcache.api import cached_property
 import voluptuous as vol
 
-from homeassistant.components import websocket_api
+from homeassistant.components import automation, websocket_api
 from homeassistant.components.blueprint import CONF_USE_BLUEPRINT
+from homeassistant.components.labs import async_listen as async_labs_listen
 from homeassistant.const import (
     ATTR_ENTITY_ID,
     ATTR_MODE,
@@ -280,6 +281,21 @@ async def async_setup(hass: HomeAssistant, config: ConfigType) -> bool:
     hass.services.async_register(
         DOMAIN, SERVICE_TOGGLE, toggle_service, schema=SCRIPT_TURN_ONOFF_SCHEMA
     )
+
+    @callback
+    def new_triggers_conditions_listener() -> None:
+        """Handle new_triggers_conditions flag change."""
+        hass.async_create_task(
+            reload_service(ServiceCall(hass, DOMAIN, SERVICE_RELOAD))
+        )
+
+    async_labs_listen(
+        hass,
+        automation.DOMAIN,
+        automation.NEW_TRIGGERS_CONDITIONS_FEATURE_FLAG,
+        new_triggers_conditions_listener,
+    )
+
     websocket_api.async_register_command(hass, websocket_config)
 
     return True
diff --git a/tests/components/script/test_init.py b/tests/components/script/test_init.py
index ff068d6f952..a0cf18b8785 100644
--- a/tests/components/script/test_init.py
+++ b/tests/components/script/test_init.py
@@ -7,7 +7,7 @@ from unittest.mock import ANY, Mock, patch
 
 import pytest
 
-from homeassistant.components import script
+from homeassistant.components import labs, script
 from homeassistant.components.script import DOMAIN, EVENT_SCRIPT_STARTED, ScriptEntity
 from homeassistant.config_entries import ConfigEntryState
 from homeassistant.const import (
@@ -1868,3 +1868,64 @@ async def test_script_queued_mode(hass: HomeAssistant) -> None:
 
     await hass.services.async_call("script", "test_main", blocking=True)
     assert calls == 4
+
+
+async def test_reload_when_labs_flag_changes(
+    hass: HomeAssistant,
+    hass_ws_client: WebSocketGenerator,
+) -> None:
+    """Test scripts are reloaded when labs flag changes."""
+    event = "test_event"
+    hass.states.async_set("test.script", "off")
+
+    ws_client = await hass_ws_client(hass)
+
+    assert await async_setup_component(
+        hass,
+        "script",
+        {
+            "script": {
+                "test": {
+                    "sequence": [
+                        {"event": event},
+                        {"wait_template": "{{ is_state('test.script', 'on') }}"},
+                    ]
+                }
+            }
+        },
+    )
+    assert await async_setup_component(hass, labs.DOMAIN, {})
+
+    assert hass.states.get(ENTITY_ID) is not None
+    assert hass.services.has_service(script.DOMAIN, "test")
+
+    for enabled, active_object_id, inactive_object_ids in (
+        (False, "test2", ("test",)),
+        (True, "test3", ("test", "test2")),
+    ):
+        with patch(
+            "homeassistant.config.load_yaml_config_file",
+            return_value={
+                "script": {active_object_id: {"sequence": [{"delay": {"seconds": 5}}]}}
+            },
+        ):
+            await ws_client.send_json_auto_id(
+                {
+                    "type": "labs/update",
+                    "domain": "automation",
+                    "preview_feature": "new_triggers_conditions",
+                    "enabled": enabled,
+                }
+            )
+
+            msg = await ws_client.receive_json()
+            assert msg["success"]
+            await hass.async_block_till_done()
+
+        for inactive_object_id in inactive_object_ids:
+            state = hass.states.get(f"script.{inactive_object_id}")
+            assert state.attributes["restored"] is True
+            assert not hass.services.has_service(script.DOMAIN, inactive_object_id)
+
+        assert hass.states.get(f"script.{active_object_id}") is not None
+        assert hass.services.has_service(script.DOMAIN, active_object_id)